Children with Cholestatic Liver Disease: Diagnostics

Cholestatic Jaundice is a rare presentation of various hepatobiliary, metabolic, and genetic disorders. Cholestasis typically presents in the neonatal/infantile period but can also present late in older children or even adults. Early diagnosis and appropriate management of the underlying condition are of paramount importance for optimal prognosis. Diagnosis of cholestasis needs an array of investigations including blood tests, imaging, genetic testing, and invasive procedures like liver biopsy. Liver biopsy is one of the central crucial investigations done in evaluating children with cholestasis, however, can be associated with complications including bleeding. Understanding when to use a liver biopsy in children with cholestasis along with its limitations is extremely important to gain the maximum benefit out of an invasive procedure. Over the last decade, the growth in genetic techniques and the identification of new genes leading to cholestasis in children have evolved significantly and have led to the shrinking of the unidentified etiologies.

In this webinar, we will discuss when to perform a liver biopsy, its utility, and limitations. We will also discuss in-depth the rapidly evolving field of Genetic Cholestasis.

Supported by educational grants from Albireo, Mirum and Travere.

Saeed Mohammad, MD, MS (Moderator)

Associate Professor of Pediatrics Pediatric Gastroenterology, Hepatology, and Nutrition

Director, Pediatric Solid Organ Transplant Center, MCJCHV Vanderbilt University Medical Center

Samar Ibrahim, M.B.Ch.B, NASPGHAN-F (Moderator)

Consultant, Division of Pediatric Gastroenterology & Hepatology Associate Professor of Pediatrics and Physiology

Medical Director Pediatric Liver Transplant Program Mayo Clinic

Mohit Kehar, MD (Moderator)

Pediatric Gastroenterologist and Hepatologist Lead Pediatric NAFLD

Children’s Hospital of Eastern Ontario

Binita M. Kamath, MBBChir MRCP MTR

Division Head (interim) Fellowship Program Director Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children

Senior Associate Scientist, Research Institute Professor, University of Toronto

Saul J. Karpen MD PhD, FAASLD

Raymond F. Schinazi Distinguished Biomedical Chair Professor of Pediatrics

Division Chief, Pediatric Gastroenterology, Hepatology and Nutrition Emory University School of Medicine & Children's Healthcare of Atlanta

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LIVE Webinar: Children with Cholestatic Liver Disease: Diagnostics
08/17/2022 at 8:00 PM (EDT)   |  120 minutes
08/17/2022 at 8:00 PM (EDT)   |  120 minutes LIVE Webinar: Children with Cholestatic Liver Disease: Diagnostics
Post-Test: Children with Cholestatic Liver Disease: Diagnostics
4 Questions  |  Unlimited attempts  |  3/4 points to pass
4 Questions  |  Unlimited attempts  |  3/4 points to pass
Post-Webinar Evaluation: Children with Cholestatic Liver Disease: Diagnostics
14 Questions
14 Questions Post-Webinar Evaluation: Children with Cholestatic Liver Disease: Diagnostics
CME Certificate: Children with Cholestatic Liver Disease: Diagnostics
1.00 CME credit  |  Certificate available
1.00 CME credit  |  Certificate available
MOC Part II Certificate: Children with Cholestatic Liver Disease: Diagnostics
1.00 MOC Part II credit  |  Certificate available
1.00 MOC Part II credit  |  Certificate available